Reversed-phase high performance liquid chromatography for the determination of N-(alpha-pyridyl) phenothiazine and N-phenylphenothiazine from the photo-simulated S(RN)1 reaction

Authors
Liu, HR Zhang, Z Zhang, L Han, XG Chen, ZB Xia, ZZ
Citation
Hr. Liu et al., Reversed-phase high performance liquid chromatography for the determination of N-(alpha-pyridyl) phenothiazine and N-phenylphenothiazine from the photo-simulated S(RN)1 reaction, MICROCHEM J, 65(2), 2000, pp. 143-146
Citations number
6
Categorie Soggetti
Spectroscopy /Instrumentation/Analytical Sciences
Journal title
MICROCHEMICAL JOURNAL
ISSN journal
0026265X → ACNP
Volume
65
Issue
2
Year of publication
2000
Pages
143 - 146
Database
ISI
SICI code
0026-265X(200009)65:2<143:RHPLCF>2.0.ZU;2-P
Abstract
A new RP-HPLC method has been described for the determination of N-(alpha-p yridyl)phenothiazine and N-phenylphenothiazine from the photo-simulated S(R N)1 reaction, using a mobile phase of methanol/tetrahydrofuran/water (72:6: 22 v/v) and a C-18-column. A UV wavelength of 254 nm was used. The linear r anges were 0.05-0.7 mg/l. The R.S.D.s were smaller than 2.4%. (C) 2000 Else vier Science B.V. All rights reserved.