Determination of the neurotransmitter-norepinephrine in the presence of ascorbic acid using carbon fiber microelectrodes activated by potentiostat

Carbon fiber microelectrodes pretreated electrochemically exhibit highly el ectrochemical activity and show high sensitivity for determining of the neu rotransmitter-norepinephrine in the presence of high concentrations of asco rbic acid. The peak currents are a linear relationship with norepinephrine in the range of 639 x 10(-6)-1.06 x 10(-4) mol/l and the detection limit is up to 2.0 x 10(-6) mol/l. All analytical processes can be performed withou t deaeration. It is possible to use the electrochemically pretreated carbon fiber microelectrodes in determining norepinephrine in vivo directly. (C) 2000 Elsevier Science B.V. All rights reserved.