The distribution of herpes simplex virus type 1 (HSV-1) in human geniculate
, vestibular ganglia, and vestibular nuclei was determined in 10 human temp
oral bones and brainstems of five individuals by PCR. HSV-1 was found in 3
of 10 of each ganglia and vestibular nuclei. The various patterns of HSV-1
infection of vestibular structures are compatible with virus migration from
the vestibular ganglia to the vestibular nuclei and from the ipsilateral t
o the contralateral vestibular nucleus via commissural fibers.