Reactivation of encoding-related brain activity during memory retrieval

Neuronal models predict that retrieval of specific event information reacti vates brain regions that were active during encoding of this information. C onsistent with this prediction, this positron-emission tomography study sho wed that remembering that visual words had been paired with sounds at encod ing activated some of the auditory brain regions that were engaged during e ncoding. After word-sound encoding, activation of auditory brain regions wa s also observed during visual word recognition when there was no demand to retrieve auditory information. Collectively, these observations suggest tha t information about the auditory components of multisensory event informati on is stored in auditory responsive cortex and reactivated at retrieval, in keeping with classical ideas about "redintegration," that is, the power of part of an encoded stimulus complex to evoke the whole experience.