Background: The rationale of palliative endoscopic treatment is to avo
id a colostomy in patients with advanced disease and Limited life expe
ctancy. This study was conducted to evaluate the role of endoscopic st
ent implantation for palliation of obstructing rectal cancer. Methods:
Overall, 19 patients (aged 47-87 years) with nonresectable or metasta
tic rectal cancer were treated by stent insertion after laser recanali
zation or dilation. Three types of stents, i.e., plastic tubes (n = 8)
, self-expanding mesh stents (n = 6), and endocoil stents (n = 5), wer
e used to maintain luminal patency. Results: Endoscopic stent implanta
tion was successfully performed in all 19 patients. Long-term luminal
patency and satisfactory bowel function were achieved in 16 of 19 pati
ents (84%). After a median follow-up of 6 months, eight of the patient
s have died and eight are still alive without evidence of recurrent, o
bstruction. Dislocation of the endoprosthesis occurred in two of eight
plastic tubes and one of five mesh stents. Recurrent obstruction due
to turner in grow th was only observed in patients treated with self-e
xpanding mesh stents (n = 2). in spite of reinsertion and laser therap
y a colostomy was required in three of 19 patients. There was no evide
nce of treatment failure in five patients who received endocoil stents
. None of the patients experienced serious complications related to th
e endoscopic procedure. Conclusions: Endoscopic stent implantation see
ms to be a safe and efficient palliative approach to selected patients
with obstructing rectal cancer. Currently, self-expanding coil stents
are superior to other devices because of lower risk of dislocation an
d tumor ingrowth.