Background: The aim was to examine mortality in psychiatric patients in Wes
tern Australia (WA), over a time period of considerable change in the deliv
ery of mental health services. Methods: A population-based record linkage a
nalysis was undertaken to quantify mortality among people with mental illne
ss in WA. Mortality rates were calculated in users of mental health service
s and compared with rates in the whole population of WA. Trends in mortalit
y were also examined using relative survival analysis, and proportional haz
ards regression. Results: The overall mortality rate ratio was 2.57 in male
s (95% CI: 2.51-2.64), and 2.18 in females (2.12-2.24). The highest cause-s
pecific mortality rate ratio was for deaths due to suicide [RR: 7.37 in mal
es (95% CI: 6.74-8.05) and 8.38 in females (959/0 CI: 7.11-9.89)], with mor
tality rate ratios being significantly greater than 1 for all other major c
auses of death. A relative survival analysis found that the excess mortalit
y risk was concentrated in the first few years after first contact with men
tal health services. Proportional hazards regression analysis found a sligh
t elevation of mortality rates over time. Conclusions: Mortality among psyc
hiatric patients remains high and appears to be increasing. Highest excess
mortality rate is associated with suicide, but mortality rates are signific
antly elevated for all major causes of death.