A convenient synthetic method for fully conjugated 3-alkyl- and 3-aryl-5-trifluoromethyl-1-methyl-1,2-thiazine 1-oxide from beta-alkoxyvinyl trifluoromethyl ketones

Authors
Bonacorso, HG Bittencourt, SRT Lourega, RV Flores, AFC Zanatta, N Martins, MAP
Citation
Hg. Bonacorso et al., A convenient synthetic method for fully conjugated 3-alkyl- and 3-aryl-5-trifluoromethyl-1-methyl-1,2-thiazine 1-oxide from beta-alkoxyvinyl trifluoromethyl ketones, SYNTHESIS-S, (10), 2000, pp. 1431-1434
Citations number
14
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
SYNTHESIS-STUTTGART
ISSN journal
00397881 → ACNP
Issue
10
Year of publication
2000
Pages
1431 - 1434
Database
ISI
SICI code
0039-7881(200009):10<1431:ACSMFF>2.0.ZU;2-S
Abstract
A new series of 4-dimethylsulfoximide-1,1,1-trifluoro-3-buten-2-ones has be en prepared by the direct reaction of 4-alkoxy-4-alkyl-(aryl)-1,1,1-trifluo ro-3-buten-2ones with S,S-dimethylsulfoximide, in good yields. The new 5-tr ifluoromethylated 3-alkyl-and 3-aryl-1-methyl-1,2-thiazine 1-oxide derivati ves by intramolecular cyclization reactions have been easily isolated.