Testosterone substitution in ageing males

Hypogonadism is the main indication for testosterone substitution in the ag eing male. The choice of the testosterone preparation should be based on th e principle that serum levels of testosterone remain in the normal range an d fast termination of therapy is possible. To dare, transdermal testosteron e systems appear to be best suited for substitution therapy in the ageing m ale. future promising developments are testosterone gels and intramuscular testosterone undecanoate. Any testosterone therapy in the ageing male has t o be monitored closely, especially regarding erythropoiesis and the prostat e.