Feline leukemia virus and feline immunodeficiency virus

Feline leukemia virus and feline immunodeficiency virus are frequently asso ciated with multisystemic disease in cats. Clinical disease involving the e ye and periorbital tissues can present in a variety of forms in the cat inf ected with feline leukemia virus or feline immunodeficiency virus. Tissue d amage may occur because of direct viral effects, or the virus may predispos e the ocular tissues to secondary infections or neoplastic transformation d ue to immunomodulation. The ocular manifestations of both viral infections are reviewed.