Chorioretinal involvement in primary systemic nonfamilial amyloidosis

PURPOSE: To report a case of primary systemic nonfamilial amyloidosis studi ed by fluorescein angiography and indocyanine green angiography, METHODS: Case report. A 59-year-old woman with primary systemic nonfamilial amyloidosis presented bilateral diffuse deep hemorrhages and pigmentary mo ttling at the posterior pole. RESULTS: On fluorescein angiography bilateral diffuse areas of hypofluoresc ence were present. Indocyanine green angiography showed large hypofluoresce nt areas with hypofluorescent lines in the midperiphery and hyperfluorescen t streaks in the peripapillary area. CONCLUSIONS: Tn this case of primary systemic nonfamilial amyloidosis, diff use bilateral chorioretinal abnormalities included hemorrhages and pigmenta ry mottling at the posterior pole, with hypofluorescent areas on fluorescei n angiography and indocyanine green angiography, as well as hypofluorescent lines in the midperiphery, (C) 2000 by Elsevier Science Inc. All rights re served.