The treatment of liver injuries involves many strategies ranging from obser
vation to operative intervention and includes numerous options such as angi
ography, packing, and damage-control procedures. In July 1994 we instituted
a protocol for the management of traumatic liver injuries. The main object
ive of this study was to evaluate the management of liver injuries occurrin
g since the institution of the protocol. Two hundred three consecutive adul
t patients with liver injuries were evaluated at our Level I trauma center
between July 1994 and May 1999, Eighty-eight per cent of the injuries were
blunt with a mean Injury Severity Score (ISS) of 24.3 +/- 0.8 and a surviva
l probability (Ps) of 90.0 +/- 1.5 per cent. The overall mortality was 6.4
per cent. A comparison between patients with minor liver injuries and patie
nts with more severe injuries [Abbreviated Injury Score (AIS) <3 vs >3] dem
onstrated no difference in mortality between the two groups despite a Ps of
93.8 +/- 1.3 per cent in patients with an AIS <3 versus 84.1 +/- 3.3 per c
ent in patients with an AIS >3. The most common complication in our patient
population was posthemorrhagic anemia, which was seen in 10.8 per cent of
cases. Severity of injury did not result in a significant difference in the
complication rate. Patients who underwent laparotomy had a statistically h
igher ISS, a lower Ps, and a mortality rate of 11.5 per cent compared with
3.7 per cent (P = 0.03) in patients managed nonoperatively. However, a comp
arison of patients undergoing laparotomy with those who did not and who had
equivalent ISS demonstrated no difference in mortality. Our results demons
trated that a preplanned management strategy was a successful way in which
to treat patients with traumatic liver injuries, Although nonoperative mana
gement of liver injuries has been common practice a management plan that in
volves a multimodal surgical strategy is essential.