K. Ajito et al., Investigation of the molecular extraction process in single subpicoliter droplets using a near-infrared laser Raman trapping system, ANALYT CHEM, 72(19), 2000, pp. 4721-4725
The near-infrared (NIR) laser Raman trapping system was applied to study li
quid-liquid extraction in a single droplet in a subpicoliter range. The sys
tem trapped a single subpicoliter toluene droplet in water using the NIR la
ser beam and provided time-dependent optical images of the droplet during l
iquid-liquid extraction. The size of the trapped droplet gradually increase
d after p-nonylphenol solution was added in water. The Raman spectra of the
droplet prove that the increase of the droplet size was caused by the abso
rption of p-nonylphenol from the water. The distribution coefficient of p-n
onylphenol in the subpicoliter droplet was much higher than that in bulk so
lution.