Objective: Some prolonged and turbulent grief reactions include sympto
ms that differ from the DSM-IV criteria for major depressive disorder.
The authors investigated a new diagnosis that would include these sym
ptoms. Method: They developed observer-based definitions of 30 symptom
s noted clinically in previous longitudinal interviews of bereaved per
sons and then designed a plan to investigate whether any combination o
f these would serve as criteria for a possible new diagnosis of compli
cated grief disorder. Using a structured diagnostic interview, they as
sessed 70 subjects whose spouses had died. Latent class model analyses
and signal detection procedures were used to calibrate the data again
st global clinical ratings and self-report measures of grief-specific
distress. Results: Complicated grief disorder was found to be characte
rized by a smaller set of the assessed symptoms. Subjects selected by
an algorithm for these symptom patterns did not significantly overlap
with subjects who received a diagnosis of major depressive disorder. C
onclusions: A new diagnosis of complicated grief disorder may be indic
ated. Its criteria would include the current experience (more than a y
ear after a loss) of intense intrusive thoughts, pangs of severe emoti
on, distressing yearnings, feeling excessively alone and empty, excess
ively avoiding tasks reminiscent of the deceased, unusual sleep distur
bances, and maladaptive levels of loss of interest in personal activit
ies.