Mullerian adenosarcoma of the uterus associated with tamoxifen therapy

Mullerian adenosarcoma of the uterus is a biphasic tumor exhibiting benign epithelial and malignant stromal component. This tumor may occasionally be associated with tamoxifen therapy which is used as an adjuvant drug for bre ast carcinoma. Reviewing the literature, we found only 12 adenosarcoma case s associated with tamoxifen therapy Thus, the clinical and pathological fin dings in a 58 years old postmenopausal woman who developed uterine adenosar coma, following low dose tamoxifen therapy after 8 years, was discussed in this report.