Study on the decomposition products of thiadiazinthione and their anticancer properties

Authors
Perez, R Rodriguez, H Perez, E Suarez, M Reyes, O Gonzalez, LJ de Cerain, AL Ezpelata, O Perez, C Ochoa, C
Citation
R. Perez et al., Study on the decomposition products of thiadiazinthione and their anticancer properties, ARZNEI-FOR, 50(9), 2000, pp. 854-857
Citations number
18
Categorie Soggetti
Pharmacology & Toxicology
Journal title
ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH
ISSN journal
00044172 → ACNP
Volume
50
Issue
9
Year of publication
2000
Pages
854 - 857
Database
ISI
SICI code
0004-4172(200009)50:9<854:SOTDPO>2.0.ZU;2-5
Abstract
Study of the anticancer properties of thirty-four 3,5-disubstituted-tetrahy dro-2H-1,3,5-thiadiazin-2-thione derivatives has been carried out by using cytotoxicity assays against HeLa, HT-29 and Hep G2 cells. The decomposition products of thiadiazinthione 1m have been studied and their anticancer pro perties evaluated.