Marked therapeutic effect of dimyristoylphosphatidylcholine liposomes on carcinoma mice model in vivo

Authors
Ueoka, R Matsumoto, Y Kanno, A Tsuzaki, K Ichihara, H
Citation
R. Ueoka et al., Marked therapeutic effect of dimyristoylphosphatidylcholine liposomes on carcinoma mice model in vivo, BIOL PHAR B, 23(10), 2000, pp. 1262-1263
Citations number
10
Categorie Soggetti
Pharmacology & Toxicology
Journal title
BIOLOGICAL & PHARMACEUTICAL BULLETIN
ISSN journal
09186158 → ACNP
Volume
23
Issue
10
Year of publication
2000
Pages
1262 - 1263
Database
ISI
SICI code
0918-6158(200010)23:10<1262:MTEODL>2.0.ZU;2-U
Abstract
Significantly prolonged survival rate was obtained for the first time using carcinoma mice models after the administration of single-component liposom es of dimyristoylphosphatidylcholine (DMPC) without any drug. An increase i n lymphocytes under optical microscope was observed without ang; increase i n the neutrophils count, suggesting that the DMPC liposomes might inhibit t he tumor growth as cell as increase in lymphocytes in vivo.