Am. Farrell et al., Genital lichen sclerosus associated with morphoea or systemic sclerosis: clinical and HLA characteristics, BR J DERM, 143(3), 2000, pp. 598-603
although patients with both morphoea and lichen sclerosus have been reporte
d previously in the majority of these reports the lichen sclerosus has been
extragenital. We report nine patients in whom genital lichen sclerosus coe
xisted with scleroderma spectrum disorders including seven with morphoea, o
ne with morphoea and lichen planus, and one with systemic sclerosis, The cl
inical features, associated autoimmune disease, autoautibodies and HLA type
are reported. Antibodies to Borrelia burgdorferi were not detected in any
of the patients. The coexistence of these diseases raises a number of intri
guing questions about the relationship between them.