Ardisimamillosides C-F, four new triterpenoid saponins from Ardisia mamillata

Four new triterpenoid saponins, ardisimamilloside C (1), 3-O-(alpha-L-rhamn opyranosyl-(1 --> 2)-beta-Dglucopyranosyl-(1 --> 4)-[beta-D-glucopyranosyl- (1 --> 2)]-alpha-L-arabinopyranosyl)-3 beta,16 alpha 28,30-tetrahydroxy-ole an-12-en, ardisimamilloside D (2), 3-O-(alpha-L-rhamnopyranosyl-(1 --> 2)-b eta-D-glucopyranosyl-(1 --> 4)-[beta-D-glucopyranosyl-(1 --> 2)]-alpha-L-ar abinopyranosyl)-3 beta,15 alpha,28,30-tetrahydroxy-olean-12-en, ardisimamil loside E (3), 3-O-(alpha-L-rhamnopyranosyl-(1 --> 2)-beta-D-glucopyranosyl- (1 --> 4)-[beta-D-glucopyranosyl-(1 --> 2)]-alpha-L-arabinopyranosyl)-13 be ta,28-epoxy-3 beta,16 alpha,29-oleananetriol, and ardisimamilloside F (4), 3-O-(alpha-L-rhamnopyranosyl-(1 --> 2)-beta-D-glucopyranosyl-(1 --> 4)-[bet a-D-glucopyranosyl-(1 --> 2)]-alpha-L-arabinopyranosyl)-3 beta,16 alpha-dih ydroxy-13 beta,28-epoxy-oleanan-30-oic acid were isolated from the roots of Ardisia mamillata HANCE, Structure assignments were established on the bas is of highresolution (HR)-FAB-MS,H-1-, C-13-, and two-dimensional (2D)-NMR spectra, and on the chemical evidence.