Successful treatment of protein-losing enteropathy due to AA amyloidosis with somatostatin analogue and high dose steroid in ankylosing spondylitis

Secondary amyloidosis is an occasional complication of ankylosing spondylit is (AS) and in most eases venal amyloidosis presents with proteinuria, neph rotic syndrome and decreased renal function. WE describe a 32-year-old male patient with AS manifested by frequent diarrhea, intermittent abdominal pa in and low serum albumin levels. He has suffered from severe inflammatory b ack pain for 14 years with multiple peripheral joint involvement. Protein-l osing enteropathy due to gastrointestinal amyloidosis was diagnosed with (9 9)mTc-human albumin scintigraphy, fecal alpha-1 antitrypsin clearance and c olonoscopic biopsy with Congo I-ed staining. Somatostatin analogue octreoti de and prednisolone were introduced with successful result.