Physical injury as a provoking factor in three patients with scleroderma

A 51-year-old female developed linear like scleroderma in the left thigh fo llowing a linear wound caused by a car accident. 27 years Inter she also de veloped a typical diffuse cutaneous systemic sclerosis with extensive skirt involvement and bibasilar pulmonary fibrosis. The second case is a 39-year -old-female who had a history of Raynaud's phenomenon since early childhood . She developed a morphea following a burning injury of the left thigh. 17 years later she also developed a typical limited cutaneous systemic scleros is with sclerodactyly, skin ulcers and subcutaneous calcinosis. The third c ase is a 43-year-old female who developed a typical morphea of the right el bow around the site of a previous local corticosteroid injection. The two r emarkable points of these 3 cases are the possible role of physical injury, in the provocation of localized scleroderma and in the first 2 cases the u nusual later development of a systemic form of scleroderma.