Pulp revascularization of replanted immature dog teeth after different treatment methods

The purpose of the present study was to determine the effect of topical tre atment with doxycycline and,/or the application of unfilled resin to the an atomical crown on the occurrence of revascularization in reimplanted dog te eth. Ninety-six teeth in 4 young mongrel dogs were used. Eighty one teeth w ere atraumatically extracted and divided into four groups. Group 1, 17 teet h were kept dry for 5 min and then replanted. Group 2, 21 teeth were soaked with a freshly prepared solution of doxycycline (1 mg/20 mL saline) for 5 min before replantation. Group 3, 23 teeth were soaked with the doxycycline solution for 5 min, and then replanted. The crowns were coated with 2 laye rs of light cured unfilled resin. Group 4, 20 teeth were kept dry for 5 min , and then replanted. The crowns were treated as with the teeth in Group 3. Three months after surgery, radiographic evaluation revealed that 27 teeth had continued root development and 32 teeth showed arrested root developme nt with periradicular pathosis. The remaining 17 teeth, which had arrested root development but no signs of periradicular pathosis, were all histologi cally evaluated for final assessment. The occurrence of revascularization a ccording to treatment group was 29.4%, 60%, 60%, 36.8% in Group 1, 2, 3, an d 4, respectively. A multiple logistic regression analysis in SAS indicated there was no significant association between vitality and dog (P=0.7564). Soaking for 5 min in doxycycline significantly increased the revascularizat ion rate (P=0.024) while the addition of resin to the crown did not result in an increased incidence of pulp revascularization (P=0.823).