Objective: To evaluate the benefits and indications for amniocentesis in ca
ses of preterm labor with or without preterm rupture of membranes. Method:
A review of the literature on amniocentesis in cases of intra-amniotic infe
ction. Results: Amniocentesis is an invasive method that allows the diagnos
is of intra-amniotic infection. However, no randomized trials have been per
formed from which we can assess the benefits and complications of amniocent
esis in preterm labor. Conclusion: The published data do not justify the ro
utine practice of amniocentesis in preterm labor. More data are needed to e
valuate the benefits and complications of this practice. Only randomized tr
ials of patients in preterm labor, comparing those who undergo amniocentesi
s with those who do not, will clarify the indications for this procedure. (
C) 2000 Elsevier Science Ireland Ltd. All rights reserved.