Vascularized pigment epithelial detachment in adult-onset foveomacular vitelliform dystrophy

PURPOSE. TO report a case showing adult-onset foveomacular vitelliform dyst rophy (AOFVD), associated with vascularized pigment epithelial detachment. CASE REPORT. A 72-year-old female affected by AOFVD complained with blurred vision and metamorphopsia in her right eye, seven months after a routinary clinical examination. Visual acuity in right eye dropped from 0.6 to 0.3, and biomicroscopic fundus examination revealed a serous pigment epithelial detachment arising from the temporal margin of the pseudovitelliform lesion . Fluorescein angiography showed an uneven filling of the pigment epithelia l detachment, suggesting the presence of a subfoveal choroidal neovasculari sation, which was confirmed by indocyanine green angiography. DISCUSSION. The association between AOFVD and vascularized pigment epitheli al detachment, supports the hypothesis that AOFVD may be a different subgro up of age-related macular degeneration with specific genetic predisposition .