Power Doppler ultrasound of gallbladder wall vascularization in inflammation: clinical implications

We investigated the role of Power Doppler US in the diagnosis and follow-up of cholecystitis. We reviewed the examinations of 21 surgical patients age d 27-48 years with US findings of cholecystitis. We performed B-mode and th en Power Doppler US. Wall thickness and US structure, the presence of stone s, and US Murphy's sign were assessed at B-mode US, whereas only the presen ce/absence of wall vascularization was studied with Power Doppler. B-mode a nd Power Doppler changes post treatment were also investigated. Ultrasound showed wall thickening in all patients. In addition, positive Murphy's sign and/or gallbladder stones were seen in 6 patients each at B-mode US and wa ll vascularization in 7 patients with Power Doppler. Acute cholecystitis wa s diagnosed in these patients. The other 14 patients presenting wall thicke ning but no vascularization and negative US Murphy's sign were diagnosed as having chronic cholecystitis; 10 of them had gallbladder stones. Two of se ven acute cholecystitis patients were operated on in the acute stage for th e onset of complications and histologic findings confirmed the US diagnosis . As for the remaining patients, histology diagnosed chronic cholecystitis in 17, whereas wall thickening was not inflammatory in 2 cases. All the cas es with early wall vascularization were eventually diagnosed as cholecystit is. Power Doppler US permits confirmation of the diagnosis of acute cholecy stitis and distinguishing of chronic disease, which helps in planning of su rgery.