Investigating development of infective stage larvae of filarial nematodes

Lymphatic filariasis is a parasitic disease affecting millions of individua ls and one of the leading causes of disability in the world. However, consi dering the magnitude of filariasis as a public health problem, relatively l ittle is known about the basic biology of the disease and its causative age nts, filarial nematodes. In this paper, the biology of the infective stage larvae of the nematodes responsible for lymphatic filariasis and the approa ches used to study their development are reviewed.