There is generally a dearth of evidence of the nature of Quaternary cl
imate change within desert systems, which has limited precious interpr
etations of past environmental change at low latitudes. The Last Glaci
al Maximum has previously been identified as the peak of Late Quaterna
ry aridity, when desert systems expanded to five times their present e
xtent(1-3), and low-latitude aridity has been described for previous g
laciations(4). But little evidence has been derived directly for large
desert basins, particularly southern Africa. Here we report new chron
ological (optical dating) evidence of arid episodes recorded in aeolia
n sediments from the Mega Kalahari sand sea. Episodic aeolian activity
is recorded at the northeastern desert margin, whereas more sustained
activity is evident from the southwestern desert core. Several signif
icant arid events are apparent since the last interglacial period, wit
h dune-building (arid) phases at similar to 95-115, 41-46, 20-26 and 9
-16kyr before present. Existing atmospheric general circulation model
simulations and independent palaeoclimate data indicate that the chang
es in aridity are related to changes in the northeast-southwest summer
rainfall gradient, which are in turn related to sea surface temperatu
res in the southeastern Atlantic Ocean.