Although computed tomography (CT) is not routinely indicated in uncomp
licated renal infection, it is of value in establishing the diagnosis
in equivocal cases, in evaluating high-risk patients, and in determini
ng the extent of disease, Unenhanced CT is useful in demonstrating gas
, calculi, parenchymal calcifications, hemorrhage, and inflammatory ma
sses, However, a contrast material-enhanced study is essential for com
plete evaluation of patients with renal inflammatory disease to demons
trate alterations in renal excretion of contrast material that occur a
s a result of the inflammatory process, In severe acute pyelonephritis
, enhanced CT scans obtained during the cortical nephrographic phase t
ypically demonstrate solitary or multifocal areas of hypoattenuation w
ith loss of the corticomedullary interface, Delayed CT scans obtained
during the excretory phase are frequently more helpful than early CT s
cans in defining the extent of the disease process, identifying compli
cations such as renal abscess, and confirming the presence of urinary
obstruction.