Multiblock copolymers based on segments of poly (D,L-lactic-glycolic acid)and poly(ethylene glycol) or poly(epsilon-caprolactone): A comparison of their thermal properties and degradation behavior

Authors
Penco, M Bignotti, F Sartore, L D'Antone, S D'Amore, A
Citation
M. Penco et al., Multiblock copolymers based on segments of poly (D,L-lactic-glycolic acid)and poly(ethylene glycol) or poly(epsilon-caprolactone): A comparison of their thermal properties and degradation behavior, J APPL POLY, 78(10), 2000, pp. 1721-1728
Citations number
31
Categorie Soggetti
Organic Chemistry/Polymer Science","Material Science & Engineering
Journal title
JOURNAL OF APPLIED POLYMER SCIENCE
ISSN journal
00218995 → ACNP
Volume
78
Issue
10
Year of publication
2000
Pages
1721 - 1728
Database
ISI
SICI code
0021-8995(200012)78:10<1721:MCBOSO>2.0.ZU;2-T
Abstract
A comparison of the thermal properties of two classes of poly(D,L-lactic-gl ycolic acid) multiblock copolymers is reported. In particular, the results of differential scanning calorimetry, and thermogravimetric analysis of cop olymers containing poly(ethylene glycol) (PEG) or diol-terminated poly(epsi lon-caprolactone) (PCDT) segments are described. The influence of the chemi cal structure and the length of PEG and PCDT on thermal stability, degree o f crystallinity and glass transition temperature (T-g) is discussed. Finall y, an evaluation of the hydrolytic behavior in conditions mimicking the phy siological environment is reported. (C) 2000 John Wiley & Sons, Inc.