On 3-D graphical representation of DNA primary sequences and their numerical characterization

In this article we (1) outline the construction of a 3-D "graphical" repres entation of DNA primary sequences, illustrated on a portion of the human be ta globin gene; (2) describe a particular scheme that transforms the above 3-D spatial representation of DNA into a numerical matrix representation; ( 3) illustrate construction of matrix invariants for DNA sequences; and (4) suggest a data reduction based on statistical analysis of matrix invariants generated for DNA. Each of the four contributions represents a novel devel opment that I we hope will facilitate comparative studies of DNA and open n ew directions for representation and characterization of DNA primary sequen ces.