A new route to 2,3-dihydro-1,5-benzothiazepines from nitrodisulfides and alpha,beta-unsaturated ketones by SmI2

Authors
Chen, XY Zhong, WH Zhang, YM
Citation
Xy. Chen et al., A new route to 2,3-dihydro-1,5-benzothiazepines from nitrodisulfides and alpha,beta-unsaturated ketones by SmI2, J CHEM R-S, (8), 2000, pp. 386-387
Citations number
23
Categorie Soggetti
Chemistry
Journal title
JOURNAL OF CHEMICAL RESEARCH-S
ISSN journal
03082342 → ACNP
Issue
8
Year of publication
2000
Pages
386 - 387
Database
ISI
SICI code
0308-2342(200008):8<386:ANRT2F>2.0.ZU;2-Z
Abstract
Nitrodisulfides on treatment with SmI2, in anhydrous THF at room temperatur e lead to reactive intermediates, which are: "living" double-anions and rea ct smoothly with alpha,beta-unsaturated ketones to afford 2,3-dihydro-1,5-b enzothiazepines in good yields under mild and neutral conditions.