A. De Zoysa et A. Efstratiou, Use of amplified fragment length polymorphisms for typing Corynebacterium diphtheriae, J CLIN MICR, 38(10), 2000, pp. 3843-3845
Amplified fragment length polymorphism (AFLP) was investigated for the diff
erentiation of Corynebacterium diphtheriae isolates. Analysis using Taxotro
n revealed 10 distinct AFLP profiles among 57 isolates. Strains with riboty
pe patterns D1, D4, and D12 could not be distinguished; however, the techni
que discriminated isolates of ribotype patterns D3, D6, and D7 further. AFL
P mas rapid, fairly inexpensive, and reproducible and could be used as an a
lternative to ribotyping.