Cloning, characterization, and expression analysis of mouse enamelysin

Authors
Caterina, J Shi, J Sun, X Qian, Q Yamada, S Liu, Y Krakora, S Bartlett, JD Yamada, Y Engler, JA Birkedal-Hansen, H Simmer, JP
Citation
J. Caterina et al., Cloning, characterization, and expression analysis of mouse enamelysin, J DENT RES, 79(9), 2000, pp. 1697-1703
Citations number
17
Categorie Soggetti
Dentistry/Oral Surgery & Medicine","da verificare
Journal title
JOURNAL OF DENTAL RESEARCH
ISSN journal
00220345 → ACNP
Volume
79
Issue
9
Year of publication
2000
Pages
1697 - 1703
Database
ISI
SICI code
0022-0345(200009)79:9<1697:CCAEAO>2.0.ZU;2-M
Abstract
Enamelysin is a recently isolated member of the matrix metalloproteinase (M MP) family of extracellular matrix (ECM)-degrading enzymes. Here we describ e the isolation and characterization of the mouse enamelysin cDNA. Expressi on of mouse enamelysin was detectable only in ameloblasts and odontoblasts of developing teeth. Characterization of mouse enamelysin demonstrated that it is highly conserved in both its sequence content and pattern of express ion relative to the porcine, human, and bovine homologues previously descri bed.