Depth from defocus involves estimating the relative blur between a pair of
defocused images of a scene captured with different lens settings. When a p
riori information about the scene is available, it is possible to estimate
the depth even from a single image. However, experimental studies indicate
that the depth estimate improves with multiple observations. We provide a m
athematical underpinning to this evidence by deriving and comparing the the
oretical bounds for the error in the estimate of blur corresponding to the
case of a single image and for a pair of defocused images. A nem theorem is
proposed that proves that the Cramer-Rao bound on the variance of the erro
r in the estimate of blur decreases with an increase in the number of obser
vations. The difference in the bounds turns out to be a function of the rel
ative blurting between the observations. Hence one can indeed get better es
timates of depth from multiple defocused images compared with those using o
nly a single image, provided that these images are differently blurred. Res
ults on synthetic as well as real data are given to further validate the cl
aim. (C) 2000 Optical Society of America [S0740-3232(00)02310-3]. OCIS code
s: 150.5670, 150.6910, 100.3190, 100.2960.