Objective: To perform quantitative analysis of pathological changes in the
tympanic membrane using video-otoscopic images, Study Design: Prospective c
ase-control study. Methods: Forty-two ears of children with chronic otitis
media with effusion (OME) and 15 ears of normal children mere included in t
his study. Tympanic membrane images mere captured and digitized using a Wel
ch-Allyn (Skaneatales Falls, NY) VDX-300 Illumination and Imaging system wi
th S-VRS input to a MURO DC 30 (Pinnacle Systems, Mountain View, CA) visual
board in a Power PC-based computer. These images were visualized and recor
ded during static and pneumatic pressure changes. Quantitative analysis of
tympanic membrane disease was performed using Image Pro Plus Imaging softwa
re (Media Cybernetics, Del Mar, CA). The measurements included area of the
tympanic membrane and its quadrants, area of tympanic membrane involved by
disease, angle formed at the umbo, and length of the malleus versus vertica
l length of the tympanic membrane. Results: Tympanosclerosis was present in
57% of ears and occurred most frequently in the anteroinferior quadrant, b
ut the maximum area of involvement was in the posteroinferior quadrant. The
ratio of the angles formed at the umbo was significantly greater (P = .01)
for the OME group compared with the control group. The ratio of the length
of the umbo and the vertical length of the tympanic membrane was almost id
entical for the OME and the control groups (P = .4). Conclusions: Video-oto
scopic images can be used for quantitative analysis of tympanic membrane di
sease. The ratio of the posterior angle to the anterior angle formed at the
umbo seems to be a more reliable indicator of post otitis media than is a
reduced length of the long process of malleus.