Background: The term "Castleman's disease" (angiofollicular lymph node hype
rplasia) comprises a heterogeneous clinicopathologic entity among lymphopro
liferative disorders.
Case Report: We present a rare case with retroperitoneal manifestations, an
d discuss several aspects of diagnosis, differential diagnosis, the: clinic
al course and therapy of the disease. Finally, we summarize the actual know
ledge about the pathogenesis of Castleman's disease.