Evaluation of outcome and QOL in patients with craniofacial resection for malignant tumors involving the anterior skull base

The purpose of this study was to retrospectively evaluate the effectiveness of anterior craniofacial resection in the treatment of nasal and paranasal malignant tumors involving anterior skull base. Between 1992 and 1998, 13 patients with nasal or paranasal malignant tumors underwent this surgical p rocedure. The site and time of metastasis or recurrence, and survival outco me were retrospectively surveyed Current status of long-surviving patients and their subjective assessment of the surgical treatment were also evaluat ed through questionnaires. Median follow-up period was 52 months. Nine pati ents (69%) were alive with no evidence of disease. Of these patients, eight had survived for more than three years. Recurrence or metastasis occurred in four patients (31%). The mean time interval between surgery and recurren ce or metastasis was 11 months. According to the results of questionnaires to long-surviving patients, 89% patients had some complaints. In particular , complaints of unsightly appearance were manifested by all those patients. When the patients themselves evaluated their current conditions resulting from this surgical treatment, 63% were dissatisfied These results suggest t hat this surgical treatment is valid for selected patients in regard to sur vival outcome. When the effectiveness of this treatment is evaluated howeve r, psychological and functional issues should not be taken lightly.