The management of metastatic disease in the humerus requires consideration
of many factors. An understanding of the disease process, attention to the
principles of biopsy, and careful evaluation of the patient's general condi
tion and location and degree of bone destruction are critical elements in d
etermining treatment. Treatment should be individualized and requires a mul
tidisciplinary approach to select a strategy that will alleviate pain and o
ptimize function.