POLYMERIZABLE DENDRIMERS .3. SYNTHESIS AND POLYMERIZATION OF N-METHACRYLOYL UREA DERIVATIVES BEARING BRANCHED ASPARTIC-ACID CONDENSATES

A convergent synthesis was used to build up dendrimeric structure cons isting of L-aspartic acid units. The bifunctional monomer N-methacrylo yl-N'-succinoyl urea (3) was synthesized by addition of the free amino group of L-aspartic acid to methacryloyl isocyanate. Dendrimers of di fferent generation were prepared by condensation of the branched pepti des with the methacrylic monomer resulting in -N'-alpha,beta-bis-(L-di methoxyaspartyl)-succinoyl urea and a,beta-bis-(L-aspartyl-alpha,beta- bis-(L-dimethoxy aspartyl))-succinoyl) urea (6). The monomers were hom opoymerized and copolymerized with phenyl methacrylate and phenyl meth acrylamide by free radical mechanism.