Context: No data have been published on the relationship between advanced c
ardiac life support (ACLS) training of the individual who initiates resusci
tation efforts and survival to discharge. Objective: To determine whether p
atients whose arrests were discovered by nurses trained in ACLS had surviva
l rates different from those discovered by nurses not trained in ACLS. Desi
gn: Cohort case-comparison. Setting: A 550-bed, tertiary care center in cen
tral Georgia. Subjects: Patients whose cardiopulmonary arrest was discovere
d by a nurse who activated the in-hospital resuscitation mechanism. Main ou
tcome measure: Patient survival to discharge. Results: Initial rhythm was s
trongly related to survival to discharge and individually associated with 5
7% of the variability in survival. Nurse's training in advanced cardiac lif
e support was also strongly related to survival and individually associated
with 29% of the variability. Combining both the variables determined 62% o
f the variability in survival to discharge. Patients discovered by an ACLS-
trained nurse (n = 88) were about four times more likely to survive (33 sur
vivors, 38%) than were patients, discovered by a nurse without training in
ACLS (n = 29, three survivors, 10%). Conclusion: Arrest discovery by nurses
trained in ACLS is significantly and dramatically associated with higher s
urvival-to-discharge rates. (C) 2000 Elsevier Science Ireland Ltd. All righ
ts reserved.