CHARACTERIZATION BY FISH OF A T(5-13) IN A PATIENT WITH BILATERAL RETINOBLASTOMA

Authors
TRIVINO E GUITART M EGOZCUE J COLL MD
Citation
E. Trivino et al., CHARACTERIZATION BY FISH OF A T(5-13) IN A PATIENT WITH BILATERAL RETINOBLASTOMA, Cancer genetics and cytogenetics, 96(1), 1997, pp. 23-25
Citations number
8
Categorie Soggetti
Oncology,"Genetics & Heredity
Journal title
Cancer genetics and cytogenetics → ACNP
ISSN journal
01654608
Volume
96
Issue
1
Year of publication
1997
Pages
23 - 25
Database
ISI
SICI code
0165-4608(1997)96:1<23:CBFOAT>2.0.ZU;2-C
Abstract
We have used fluorescence in situ hybridization (FISH) with a biotinyl ated cosmid probe (13q14) to screen 25 unrelated cases with bilateral retinoblastoma and one case with unilateral retinoblastoma. In 25 case s no deletion or chromosome rearrangements were found. One constitutio nal mutation resulting from a de novo balanced chromosome translocatio n (5;13) in a patient with bilateral retinoblastoma was detected. (C) Elsevier Science Inc., 1997.