PIGMENTED CHOROID-PLEXUS CARCINOMA - A CYTOGENETIC AND ULTRASTRUCTURAL-STUDY

Authors
DOBIN SM DONNER LR
Citation
Sm. Dobin et Lr. Donner, PIGMENTED CHOROID-PLEXUS CARCINOMA - A CYTOGENETIC AND ULTRASTRUCTURAL-STUDY, Cancer genetics and cytogenetics, 96(1), 1997, pp. 37-41
Citations number
21
Categorie Soggetti
Oncology,"Genetics & Heredity
Journal title
Cancer genetics and cytogenetics → ACNP
ISSN journal
01654608
Volume
96
Issue
1
Year of publication
1997
Pages
37 - 41
Database
ISI
SICI code
0165-4608(1997)96:1<37:PCC-AC>2.0.ZU;2-7
Abstract
A pigmented choroid plexus carcinoma was studied. The pigment was Font ana-positive, and the neoplastic cells focally expressed melanosomal m arker HMB45 and contained probable aberrant melanosomes. The tumor was composed of two pseudodiploid clones, having the karyotypes 22),t(19; 22)(q13.4;q11.2)[15]/46,XY,t(4;14)(q31.1; p11.2),t(12;13)(p11.2;q34)[6 ]. The available data seem to indicate that rearrangements of 7p11-12, 9q11-12, 15q22, and 19q13.4 may play a role in the development of cho roid plexus carcinomas. (C) Elsevier Science Inc., 1997.