Reaction of 3-methylamino-1,2-diols with dihalomethanes. Synthesis of chiral 4-substituted 3-methyltetrahydro-1,3-oxazin-5-ols

Authors
Hajji, C Testa, ML de la Salud-Bea, R Zaballos-Garcia, E Server-Carrio, J Sepulveda-Arques, J
Citation
C. Hajji et al., Reaction of 3-methylamino-1,2-diols with dihalomethanes. Synthesis of chiral 4-substituted 3-methyltetrahydro-1,3-oxazin-5-ols, TETRAHEDRON, 56(41), 2000, pp. 8173-8177
Citations number
22
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
56
Issue
41
Year of publication
2000
Pages
8173 - 8177
Database
ISI
SICI code
0040-4020(20001006)56:41<8173:RO3WDS>2.0.ZU;2-I
Abstract
Enantiomerically pure 4,5-disubstituted 3-methyltetrahydro-1,3-oxazines hav e been obtained by reaction of 3-methylamino-1,2-diols with dichloromethane by regioselective differentiation of hydroxyl groups. (C) 2000 Published b y Elsevier Science Ltd.