alpha-melanocyte-stimulating hormone in normal human physiology and disease states

Authors
Catania, A Airaghi, L Colombo, G Lipton, JM
Citation
A. Catania et al., alpha-melanocyte-stimulating hormone in normal human physiology and disease states, TRENDS ENDO, 11(8), 2000, pp. 304-308
Citations number
59
Categorie Soggetti
Endocrinology, Nutrition & Metabolism
Journal title
TRENDS IN ENDOCRINOLOGY AND METABOLISM
ISSN journal
10432760 → ACNP
Volume
11
Issue
8
Year of publication
2000
Pages
304 - 308
Database
ISI
SICI code
1043-2760(200010)11:8<304:AHINHP>2.0.ZU;2-H
Abstract
Over the past two decades, research in animal models has indicated that alp ha-melanocyte-stimulating hormone (alpha-MSH) has potent anti-inflammatory properties. Furthermore, recent data show that the peptide has antimicrobia l Effects and probably contributes to innate immunity. alpha-MSH, which is produced by many extrapituitary human cells, should no longer be considered solely a pituitary hormone; rather, it should be viewed as a ubiquitous mo dulatory peptide.