Dendrimers with attached helical peptides

Authors
Higashi, N Koga, T Niwa, I
Citation
N. Higashi et al., Dendrimers with attached helical peptides, ADVAN MATER, 12(18), 2000, pp. 1373-1375
Citations number
19
Categorie Soggetti
Multidisciplinary,"Material Science & Engineering
Journal title
ADVANCED MATERIALS
ISSN journal
09359648 → ACNP
Volume
12
Issue
18
Year of publication
2000
Pages
1373 - 1375
Database
ISI
SICI code
0935-9648(20000915)12:18<1373:DWAHP>2.0.ZU;2-L
Abstract
The attachment of peptides to the surface of spherical dendrimers via graft polymerization is described here (see Figure). It is shown that the result ing peptide dendrimers display greatly enhanced helicity compared to non-de ndrimer-based analogues. This is attributed to aggregation of peptide segme nts on the dendrimer surface.