Vertical partial laryngectomy versus supracricoid partial laryngectomy forselected carcinomas of the true vocal cord classified as T2N0

Citation
O. Laccourreye et al., Vertical partial laryngectomy versus supracricoid partial laryngectomy forselected carcinomas of the true vocal cord classified as T2N0, ANN OTOL RH, 109(10), 2000, pp. 965-971
Citations number
25
Categorie Soggetti
Otolaryngology,"da verificare
Journal title
ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY
ISSN journal
00034894 → ACNP
Volume
109
Issue
10
Year of publication
2000
Part
1
Pages
965 - 971
Database
ISI
SICI code
0003-4894(200010)109:10<965:VPLVSP>2.0.ZU;2-J
Abstract
From an inception cohort of 204 patients with squamous cell carcinoma of th e true vocal cord classified as T2N0 and a minimum of 3 years of follow-up, the authors compare the oncological and functional outcomes folio wing ver tical partial laryngectomy (group 1; 85 patients) and supracricoid partial laryngectomy (group 2; 119 patients). The 10-year actuarial survival estima te was 46.2% for group 1 and 66.4% for group 2. Survival was statistically more likely to be reduced (p = .019) in group 1 than in group 2. The 10-yea r actuarial local control estimate was 69.3% for group I and 94.6% for grou p 2. Local recurrence was statistically more likely to occur (p < .0001) in group 1 than in group 2. Salvage treatment resulted in an overall 94.1% lo cal control rate and a 78.1% laryngeal preservation rate for group 1 and an overall 99.2% local control rate and a 94.9% laryngeal preservation rate f or group 2. The 10-year actuarial nodal control estimate was 81.7% for grou p 1 and 93.7% for group 2. Nodal recurrence was statistically more likely t o occur (p = .028) in group 1 than in group 2. The 10-year actuarial estima te for patients without distant metastasis was 84.6% for group 1 and 95.1% for group 2. Distant metastasis was statistically more likely to occur (p = .05) in group 1 than in group 2. The hospital mortality rate was 1.2% for group 1 and 0.8% for group 2. The incidence of permanent gastrostomy was 0% for group 1 and 2.4% for group 2. The incidence of permanent tracheostomy was 1.2% for group 1 and 2.4% for group 2. The incidence of completion lary ngectomy due to functional problems was 1.2% for group I and 0.8% for group 2.