O. Laccourreye et al., Vertical partial laryngectomy versus supracricoid partial laryngectomy forselected carcinomas of the true vocal cord classified as T2N0, ANN OTOL RH, 109(10), 2000, pp. 965-971
From an inception cohort of 204 patients with squamous cell carcinoma of th
e true vocal cord classified as T2N0 and a minimum of 3 years of follow-up,
the authors compare the oncological and functional outcomes folio wing ver
tical partial laryngectomy (group 1; 85 patients) and supracricoid partial
laryngectomy (group 2; 119 patients). The 10-year actuarial survival estima
te was 46.2% for group 1 and 66.4% for group 2. Survival was statistically
more likely to be reduced (p = .019) in group 1 than in group 2. The 10-yea
r actuarial local control estimate was 69.3% for group I and 94.6% for grou
p 2. Local recurrence was statistically more likely to occur (p < .0001) in
group 1 than in group 2. Salvage treatment resulted in an overall 94.1% lo
cal control rate and a 78.1% laryngeal preservation rate for group 1 and an
overall 99.2% local control rate and a 94.9% laryngeal preservation rate f
or group 2. The 10-year actuarial nodal control estimate was 81.7% for grou
p 1 and 93.7% for group 2. Nodal recurrence was statistically more likely t
o occur (p = .028) in group 1 than in group 2. The 10-year actuarial estima
te for patients without distant metastasis was 84.6% for group 1 and 95.1%
for group 2. Distant metastasis was statistically more likely to occur (p =
.05) in group 1 than in group 2. The hospital mortality rate was 1.2% for
group 1 and 0.8% for group 2. The incidence of permanent gastrostomy was 0%
for group 1 and 2.4% for group 2. The incidence of permanent tracheostomy
was 1.2% for group 1 and 2.4% for group 2. The incidence of completion lary
ngectomy due to functional problems was 1.2% for group I and 0.8% for group
2.