Bioabsorbable internal fixation devices were introduced clinically in the t
reatment of fractures and osteotomies of the extremities at the Department
of Orthopaedics and Traumatology, Helsinki University, in 1984. Since Novem
ber 5, 1984, a total of 3200 patients were managed using bone or ligament f
ixation devices made of self-reinforced (matrix and fibres of the same poly
mer) bioabsorbable alpha-hydroxy polyesters. The devices used included cyli
ndrical rods, screws, tacks, plugs, arrows, and wires. The most common indi
cation for the use of bioabsorbable implants was the displaced malleolar fr
acture of the ankle. Transphyseal fixation with small-diameter, mainly poly
glycolide pins was used in children. The postoperative clinical course was
uneventful in more than 90% of the patients. The complications included bac
terial wound infection in 4% and failure of fixation in 4%. In one-fifth of
the latter cases, however, re-operation was not necessary. The occurrence
of non-infectious foreign-body reactions two to three months postoperativel
y has been observed in 2% of the patients operated in the last few years wi
th polyglycolide implants but none of the patients managed with polylactide
implants. This inflammatory tissue response often required aspiration with
a needle but did not influence the functional or radiologic result of the
treatment. Owing to the biodegradability of these internal fixation devices
, implant removal procedures were avoided. This results in financial benefi
ts and psychological advantages. Bioabsorbable implants can also be used in
open fractures and infection operations. (C) 2000 Elsevier Science Ltd. Al
l rights reserved.