Cyclosporin A-related cerebral vasculopathy

Authors
Shbarou, RM Chao, NJ Morgenlander, JC
Citation
Rm. Shbarou et al., Cyclosporin A-related cerebral vasculopathy, BONE MAR TR, 26(7), 2000, pp. 801-804
Citations number
10
Categorie Soggetti
Hematology,"Medical Research Diagnosis & Treatment
Journal title
BONE MARROW TRANSPLANTATION
ISSN journal
02683369 → ACNP
Volume
26
Issue
7
Year of publication
2000
Pages
801 - 804
Database
ISI
SICI code
0268-3369(200010)26:7<801:CACV>2.0.ZU;2-Y
Abstract
The use of cyclosporin A has been associated with several side-effects, inc luding neurotoxicity. The mechanism of toxicity is not well known. We repor t two patients treated with cyclosporin A who developed lesions in the cere bral white matter associated with abnormally elevated cerebral blood flow v elocities on transcranial doppler ultrasound and abnormal vascular appearan ce on magnetic resonance angiography.