V. Piriou et al., Significance of beta-blocking agents in perioperative medicine. Part Two: Therapeutic indications, CAN J ANAES, 47(7), 2000, pp. 664-672
Citations number
79
Categorie Soggetti
Aneshtesia & Intensive Care","Medical Research Diagnosis & Treatment
Journal title
CANADIAN JOURNAL OF ANAESTHESIA-JOURNAL CANADIEN D ANESTHESIE
Purpose: To review the pharmacologic and pathophysiologic information neces
sary to prescribe beta-blockers (BB) in perioperative medicine.
Data source: Manual retrieval and electronic research of the literature usi
ng MEDLINE (key-words: anesthesia and beta- blocker; surgery and beta-block
er).
Data synthesis: In non cardiac surgery, the beneficial effects of BB have b
een demontrated in hypertensive patients since 1979. In 1996, the beneficia
l effects of atenolol in patients with coronary artery disease (reduction o
f postoperative myocardial ischemia and overall reduction in two-year morta
lity) were demonstrated, in coronary surgery, the interest of preoperative
BB treatment has been shown since 1983. Administration of BB has been shown
to be beneficial in acute myocardial infarction or chronic cardiac failure
(except in NYHA class IV patients).
Conclusion: BB have been shown to exert a beneficial effect on postoperativ
e outcomes in patients with cardiovascular disease or risk factors, and the
ir more widespread use in perioperative medicine is encouraged.