CALCIUM HYDROXIDE ROOT-CANAL SEALERS - HISTOPATHOLOGIC EVALUATION OF APICAL AND PERIAPICAL REPAIR AFTER ENDODONTIC TREATMENT

Eighty root canals of the premolars of 4 dogs, with vital pulp, were i nstrumented and filled during the same session with the Sealapex, CRCS , Sealer 26, and Apexit sealers, The animals were sacrificed 180 days after root canal filling and their maxillae and mandibles were removed and fixed in 10% formalin, After routine histologic processing, the s ections were stained with hematoxylin-eosin and Mallory trichrome, His topathologic analysis showed that Sealapex was the sealer that best pe rmitted the deposition of mineralized tissue at the apical level and w as the only sealer that provided complete sealing (37.5% of cases), Wi th the use of Sealapex, no inflammatory infiltrate occurred and there was no reabsorption of mineralized tissues, In contrast, partial seali ng and a moderate inflammatory infiltrate occurred with the use of CRC S, When Apexit and Sealer 26 were used the absence of sealing was freq uent and active reabsorption of mineralized tissues occurred in most c ases, The inflammatory infiltrate predominating with the use of Apexit was of the severe type, whereas with the use of Sealer 26 the inflamm atory infiltrate was mild or absent.