Clinical and radiological features of South African patients with tuberculomas of the brain

Intracranial tuberculomas are a rare complication of tuberculosis that typi cally occurs in immunocompromised patients not treated previously for tuber culosis. We identified tuberculomas in 12 patients (11 of whom were infecte d with human immunodeficiency virus) at a hospital in Johannesburg, South A frica. Responses to antituberculous therapy were good, often despite the pr esence of large lesions, and surgery was not considered necessary in any of the patients.